comparison of oral midazolam with intravenous midazolam for sedation children during upper gastrointestinal endoscopy
نویسندگان
چکیده
upper endoscopy is a common procedure for the diagnosis and treatment of upper digestive tract diseases. the increasing number of pediatric gastrointestinal procedures has led to increasing attention on the safety and efficacy of medications used for sedation during the procedure. this randomized blinded interventional study was designed to compare the effect of oral midazolam with intravenous (iv) midazolam as a sedative medication in 119 children undergoing endoscopy. the mean time to sedation was 2.2±0.7 in iv midazolam group and 30.9±0 in oral midazolam group which was statistically significant difference between two groups. separation from parents in oral midazolam group was as follow: 2 patients were high resistant (3.5%), 2 patients were resisted first and then relaxed (3.5%) and 55 patients were separated from their parents without any resistance (93%); whereas in iv midazolam group, 8 patients were high resistant (13.3%), 29 patients were relatively resistant (48.3%) and 23 patients were separated from their parents without any resistance (38.3%) that shows significant differences between the two groups. in terms of patient comfort during endoscopy, there was also a significant difference between the two groups. in oral midazolam, group parents were more consent, compared with the other group. the present study showed that oral midazolam is a safe and effective sedation during upper endoscopy in pediatrics. oral midazolam reducing patients' anxiety during separation from parents leads the easy use of endoscopy and comfort of patients during endoscopy as compared with iv midazolam. oral or iv midazolam were not able to put most patients in deep sedation level.
منابع مشابه
Comparison of Oral Midazolam With Intravenous Midazolam for Sedation Children During Upper Gastrointestinal Endoscopy.
Upper endoscopy is a common procedure for the diagnosis and treatment of upper digestive tract diseases. The increasing number of pediatric gastrointestinal procedures has led to increasing attention on the safety and efficacy of medications used for sedation during the procedure. This randomized blinded interventional study was designed to compare the effect of oral midazolam with intravenous ...
متن کاملComparison of oral and intra venous midazolam for sedation in children undergoing upper gastrointestinal endoscopy
Background: Selecting the best medication for upper GI endoscopy in children is a challenging issue. The goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (UGIE) on children. Methods: In this randomized clinical trial study conducted in Amirkola Children's Hospital, 110 children were randomly assigned to oral or intravenous g...
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The objectives of this study were to assess midazolam and propofol as sedative agents for outpatient gastrointestinal endoscopy, with particular reference to recovery profile, amnesic effects, and haemodynamic state and oxygenation during the procedure. Forty consecutive patients were allocated randomly to two groups. Patients in group I (n = 19) received midazolam 81 (SEM 32) micrograms kg-1; ...
متن کاملcomparison of oral and intra venous midazolam for sedation in children undergoing upper gastrointestinal endoscopy
background: selecting the best medication for upper gi endoscopy in children is a challenging issue. the goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (ugie) on children. methods: in this randomized clinical trial study conducted in amirkola children's hospital, 110 children were randomly assigned to oral or intravenous...
متن کاملUse of oral midazolam in pediatric upper gastrointestinal endoscopy.
BACKGROUND The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy. METHODS Sixty-one children (age <16 years) scheduled for upper GI endoscopy were studied. Patients were randomly assigned to receive oral or i.v. midazolam. Measurements were made and compar...
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عنوان ژورنال:
acta medica iranicaجلد ۵۴، شماره ۹، صفحات ۵۷۶-۵۸۲
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